Tag Archives: #breastcancer

Breast Cancer May Return Even 20 Years Later, Study Finds

Breast Cancer May Return Even 20 Years Later, Study Finds
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Breast cancer may return even 20 years later except if patients keep taking drugs to suppress it, researchers reported Wednesday.

They were looking for proof that at least some of the breast cancer survivors might be capable to skip the pills that decrease the risk of the breast tumors coming back but established that even women that have “low-risk” cancers had a tiny rate of reappearance 15 and even 20 years later.

This means that women with the most widespread type of breast cancer, called estrogen-positive or hormone-positive breast cancer must think cautiously about whether they want to stop taking the pills, even if they can cause some side-effects, doctors said.

“These breast cancers have a lasting smoldering quality and bear a substantial risk of late recurrence after five years of therapy,” said Dr. Harold Burstein of the Dana Farber Cancer Institute, who wasn’t involved in the study.

“A lot of patients think. ‘OK, I made it to five years. I know I’m safe’,” said Dr. Jennifer Litton, an oncologist at the MD Anderson Cancer Center. “But for estrogen-receptor positive breast cancer, it’s a constant lifelong risk.”

Breast cancer is the second-biggest cancer killer of American women, just after lung cancer. The American Cancer Society says every year; it’s diagnosed in 200,000 women and a few men and kills around 40,000.

Most types of breast cancers are fueled by estrogen, and drugs called hormone blockers are recognized to cut the risk of reappearance in such cases.

Tamoxifen long was the number one choice, but newer drugs called aromatase inhibitors — sold as Arimidex, Femara, Aromasin and in generic form — do the same job with less risk of causing uterine cancer and additional problems Longer the women is taking them, the lower their risk of having cancer come back.

Nonetheless, they do cause side-effects.

“My colleagues and I state that at the end of 5 years, the women separate themselves into two groups: those who cannot wait to get off it, and those who are frightened of getting off it and have tolerated it well,” said Dr. Eric Winer of the Dana-Farber Cancer Institute.

Melita Keith, 45, from Victoria, Texas speaks that she has been putting up with pains and aches after taking first tamoxifen and then Aromasin.

“I’ve been having pretty harsh joint pains, hot flashes, etc. In the morning, when I get out of bed I feel like I’m 90. My joints hurt,” said Keith, who was diagnosed with breast cancer when she was just 41. “On tamoxifen, I got hot flashes and pretty strong night sweats. On a scale of one to 10, I was 7.”

Breast Cancer May Return Even 20 Years Later, Study Finds

Breast Cancer May Return Even 20 Years Later, Study Finds

Keith, a patient of Litton’s, required to stop. “But if Dr. Litton tells me I must be on it, I’m staying on it. I have to be here for my kids,” added Keith, who has a daughter in 6th grade and a son in 12th grade.

Litton and Keith plan to work together to watch symptoms over the years and make a decision how long Keith will continue taking the pills.

“The idea of being considered cured if you are cancer-free for 5 years isn’t true for estrogen-positive breast cancer, even though it is true for triple-negative.”

Doctors have recognized that breast cancer can come back in a fraction of survivors. Hongchao Pan of the University of Oxford, Dr. Daniel Hayes of the University of Michigan Comprehensive Cancer Center and colleagues researched medical records of more than 80,000 women with certain types of breast cancer who were planned to take tamoxifen or similar drugs for at least five years.

“Even after 5 years women with ER-positive, early-stage breast cancer still had a constant risk of reappearance and death from breast cancer for at least 20 years after the first diagnosis,” they wrote in their report, available in the New England Journal of Medicine.

“Although these women stayed free of reappearance in the first five years, the risk of having their cancer come back elsewhere (for example in the bone, liver or lung) from years five to 20 remained constant,” Hayes said.

“I do not wish women to hear this study and think they are destined for their cancer to come back,” said Litton.

Winer said breast cancer survivors must keep an eye on their symptoms.

“If a woman develops ill-defined symptoms at year 12, and she’s being taken care of by someone not familiar with breast cancer it may take six months to get to the bottom of it,” he said.

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Should You Get Genetic Testing For The Breast Cancer Gene?

Should You Get Genetic Testing For The Breast Cancer Gene?
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If you have several people on the same side of the family with breast cancer or with other types (like  ovarian or pancreatic), or with rare cancers (such as  breast cancer in men or cancer in both breasts), or cancer diagnosed at a very early age, you might have an increased risk for breast and other types of cancers.

If you do decide to get screened—it is a simple blood or saliva test. It is important to check with a certified genetic counselor. A lot of people are familiar with the BRCA1 and BRCA2 genes, which are a warning sign of greater risk for breast and other cancers, such as ovarian, but you should know that there is a whole world of other genes that could mean the same.

Since we are discovering new genes all the time, the results—and what you must do with the information—are not at all times as clear-like with the BRCA genes, where we have years and years of research on treatment outcomes. (In that case, it may be suggested a yearly breast MRIs or risk-reducing surgeries like a bilateral mastectomy.) A genetic counselor will be present on the latest news on which genes to test for based on your family history and how to understand the sometimes foggy results.

And before you even take the test, the genetic analyst can talk about privacy concerns. A 2008 law puts a stop to discrimination based on DNA by employers and health insurance providers, but the law doesn’t cover disability, life, or long-term-care insurance. She can help you put together an informed decision.

This article initially appeared in the October 2017 issue of Women’s Health.

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Julia Louis-Dreyfus announces breast cancer diagnosis

Julia Louis-Dreyfus announces breast cancer diagnosis
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The actress shared the news on Twitter, writing, “One in eight women get breast cancer. Today, I’m the one.”

 

In spite of the tough news, we’re pleased to hear that it sounds like she is in great hands.

“The good news is that I have the most glorious group of supportive and caring family and friends, and fantastic insurance through my union,” she wrote. “The bad news is that not all women are so lucky, so let’s fight all cancers and make universal health care a reality.”

Breast cancer is in the high second place in leading cause of cancer death in women. More than 250,000 new cases will be detected in women in 2017, according to the American Cancer Society.

Fans were very fast to demonstrate their support on social media.

“Stay strong and keep fighting,” one wrote. “We love you.”

Julia Louis-Dreyfus announces breast cancer diagnosis

Mandatory Credit: Photo by Invision/AP/REX/Shutterstock (9065809g)

HBO, which recently stated “Veep” is ending, sent the next statement to The Hollywood Reporter:

“Julia received the bad news the day after the Emmys. It had no bearing in the conclusion to renew ‘Veep’ for a final season. The writers will carry on prepping as business as usual, and HBO will alter the production schedule as needed.”

“Our support and love goes to Julia and her family at this time,” the statement continued. “We have every confidence she will get through this with her usual tenacity and undaunted spirit, and look forward to her return to health and to HBO for the final season of ‘Veep.

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The Truth About Flaxseed that Every Cancer Patient Must Know

The Truth About Flaxseed that Every Cancer Patient Must Know
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We have posted before about the benefits of flaxseeds. But still, there are a lot of people who have no idea just how remarkable they are. And if you are a cancer patient? You cannot afford to miss this!

 

Flaxseeds are a remarkably jam-packed super food, filled with nutrients, fiber, vitamins, and essential fatty acids. 

Studies confirm that it can reduce your risk of cancer, heart disease, diabetes, and stroke.

 

But it may be most remarkable when it comes to cancer – and it comes down to something called lignans.  They are present in flax seeds at rates as much as 75 times higher than in any other plant food.

 

And lignans are particular cancer-fighters. Not only can they help to avoid cancer, because of their antioxidant properties, but they can, in addition, get in the way of the growth and spread of tumor cells.

 

A recent meta-analysis (Flax and Breast Cancer – A Systematic Review), which studied more than 1,800 studies involving breast cancer and flax,

 “Current evidence advocates that flax may be connected with decreased risk of breast cancer. Flax demonstrates antiproliferative effects in breast tissue of women at risk of breast cancer and may defend against primary breast cancer. Mortality risk will possibly be reduced among those living with breast cancer.”

 

Kelley C. Fitzpatrick, director of health and nutrition with the Flax Council of Canada says, recent studies have recommended that flaxseed may defend against breast cancer, prostate cancer, and colon cancer.

 

And a 2010 study available in the journal Gynecological Oncology concluded

“These findings may present the basis for a clinical trial that evaluates the efficacy of flaxseed as a chemo-suppressant of ovarian cancer in women”.

 

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Scientists in Amsterdam just destroyed breast cancer tumors in 11 days without chemo

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A new study shows a possible cure for cancer, and scientists in Europe may have discovered a breach for breast cancer.

The most widespread cancer in women, approximately 1 in 8 American women will grow it in their lifetime; the clinical trial may have discovered a way to free us of it once and for all in the future.

Breast Cancer Breakthrough

Scientists-in-Amsterdam-just-destroyed-breast-cancer-tumors-in-11-days-without-chemo

Research obtained by Professor Nigel Bundred at the European Breast Cancer Conference in Amsterdam exposed that they had tested the efficiency of a pair of drugs also known as Herceptin (a.k.a trastuzumab) and Lapatinib.

These two drugs are frequently used in breast cancer treatment by now, but this is the first time they had been joint together and used previously to surgery and chemotherapy. They were capable of getting rid of some types of breast cancer in just 11 days.

They meant to use these drugs to fight a protein called HER2 (human epidermal growth factor receptor 2), which has an effect on the growth and division of cancer cells. It’s as well more possible to come back than other cancer types.

What in addition makes this treatment so attractive is the fact that it may get rid of the need for chemotherapy and/or surgery in some of the cases.

Study Results

Scientists-in-Amsterdam-just-destroyed-breast-cancer-tumors-in-11-days-without-chemo-1

257 women with positive breast cancer HER2 were chosen for the study. In the first round, 120 women were allocated to one of three groups – some were given Herceptin (trastuzumab), others lapatinib. Both these groups were under 11 day’s treatment following diagnosis and previous to surgery.

A third group was given no drug treatment before surgery (the control group). What they discovered was that of those on the mixture of Herceptin and lapatinib, 7 of the 66 women had no remaining cancer cells within two weeks and other 11 women featured radically shrunken tumors.

In comparison to the control group who were only given Herceptin, they were discovered to have 0% with no trace of cancer cells and only 3% showed a drop in tumor size. Obviously, the two drugs united a great effect on breast cancer cells as opposite to being used on their own.

The problem at present, though, is that Herceptin’s licensing makes it only obtainable for use along chemotherapy and not alone. The outcome of this study may help to alter that though.

Even though there’s still a lot of work to be done, this is a great step in the fight against this deadly disease. With medical advancements improving, it’s completely possible this could occur sooner than we think!

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Scientists in Amsterdam Just Destroyed Breast Cancer Tumors in 11 Days Without Chemo

Scientists in Amsterdam Just Destroyed Breast Cancer Tumors in 11 Days Without Chemo
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A study presented by Professor Nigel Bundred at the European Breast Cancer Conference held in Amsterdam exposed that they had tested the success of using a pair of drugs known as Herceptin (a.k.a trastuzumab) and Lapatinib.These two drugs are usually used in breast cancer treatment by now, but this is the first time they had been mixed together and used before chemotherapy or surgery. What they discovered was they were capable to eliminate a few types of breast cancer in just 11 days.

scientists-amsterdam-just-destroyed-breast-cancer-tumors-11-days-without-chemo

Funded by Cancer Research UK, they intended to use these drugs to fight a protein called HER2 (human epidermal growth factor receptor 2) which have an effect on the growth and division of cancer cells. It’ is as well more likely to come back than other cancer types.
What also makes this treatment so tempting is the fact that it removes the need for chemotherapy and surgery. The passing side effects like vomiting, hair loss and fatigue are also avoided, making the treatment less harmful on the body. Chemo is not completely effective, or is the right choice for a many patients, so whichever alternatives are welcomed.

STUDY RESULTS

257 women that were HER2 positive breast cancer were chosen for the study; with half of them being put on the drug combo and the other half were the control group. What they discovered was that of those using the drug, 11% had no cancer cells left over within two weeks and 17% of cases featured considerably shrunken tumors.

Measured up to the control group who were only given Herceptin, they were established to have 0% with no trace of cancer cells and only 3% showed a drop in tumor size. Obviously, the two drugs mixed together have a major effect on breast cancer cells as opposite to being used on their own.

The problem at present, though, is that Herceptin’s licensing makes it only offered for use together with chemotherapy and not alone. The results from this study may help to change that.

Even though there’s still a lot of work to be done, with any luck, this is a major step in the fight against one of the deadliest diseases. With medical advancements improving each year, it’s completely possible this could happen sooner than we think!

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